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Contraindicated (one)pentobarbital will decrease the extent or outcome of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will decrease the level or outcome of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.fentanyl intranasal and pentobarbital equall